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Way et al. Onset was at birth in both. One developed hypertension at age 16 years. Kurczynski described the case of a 4-year-old girl whose father and paternal grandmother were said to be identically affected in childhood with improvement by adulthood. Shields et al.
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What is Mottled Skin: Causes, Definition, Symptoms, Diagnosis, Pictures

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Cutis marmorata telangiectatica congenita (CMTC) | Great Ormond Street Hospital

Introduction: Cutaneous decompression sickness DCS is often considered to be a mild entity that may be explained by either vascular occlusion of skin vessels by bubbles entering the arterial circulation through a right-to-left shunt or bubble formation due to saturated subcutaneous tissue during decompression. We propose an alternative hypothesis. Methods: The case is presented of a year-old female diver with skin DCS on three separate occasions following relatively low decompression stress dives. Results: There was a close similarity in appearance between the skin lesions in this woman and in other divers and those in the pigs, suggesting a common pathway. Conclusions: From this, we hypothesize that the cutaneous lesions are cerebrally mediated. Therefore, cutaneous DCS might be a more serious event that should be treated accordingly.
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Cutis marmorata telangiectatica congenita

Megalencephaly-capillary malformation syndrome MCAP is a disorder characterized by overgrowth of several tissues in the body. Its primary features are a large brain megalencephaly and abnormalities of small blood vessels in the skin called capillaries capillary malformations. In individuals with MCAP, megalencephaly leads to an unusually large head size macrocephaly , which is typically evident at birth.
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Livedo is a cutaneous sign of striking violaceous netlike patterned erythema of the skin. This dermatological phenomenon is of special interest in the differential diagnosis in neurological patients. In Ehrmann distinguished two different patterns of livedo: the pathological livedo racemosa and the physiological livedo reticularis. Despite important clinical differences, in the English language literature the heading livedo reticularis is still used for all types of livedo.
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